Self-assembly of lipopolysaccharide layers on allantoin crystals

- LPS layers self-assemble via hydrogen-bond attachment to allantoin crystals.
- Allantoin crystals bind LPS from a wide range of bacterial species.
- Binding of LPS is ∼100 stronger than for proteins and polysaccharides.
- Allantoin crystals bind nanoparticles with hydrophilic surface chemistries.
- A method for preparing solid-supported bacteria mimetic LPS layers is presented.