Effect of tetracaine on DMPC and DMPCÂ +Â cholesterol biomembrane models: Liposomes and monolayers

- Tetracaine fluidizes lipid membranes and may induce swelling or even solubilization.
- The tetracaine action depends on the membrane model and its immobilization state.
- Tetracaine affects more lipid Langmuir monolayers than liposomes in solution.
- Tetracaine affects more liposomes in solution than supported liposomes.