Novel gel-niosomes formulations as multicomponent systems for transdermal drug delivery

- The drugs percutaneous permeation profiles from LC-niosomes formulations as multicomponent systems were investigated.
- Drugs as third component in the formulations could influence the microstructure of the multicomponent system.
- Drugs percutaneous permeation from LC-niosomes systems, corresponding niosomal and LC binary systems were compared.
- All the formulation affected in different way the drugs permeation across the skin.