A centralized/decentralized control approach for periodic systems with application to chromatographic separation processes

In this work we demonstrate the application of our recently presented PAROC framework and software platform for the development of a centralized/decentralized control strategy for the twin-column Multicolumn Solvent Gradient Purification Process (MCSGP) based on multi-parametric control policies. The derived controllers are tested under the presence of disturbances, while their stability is also assessed. The proposed control approach is evaluated under an in-silico, ‘closed-loop’ fashion against the process model. The designed controller captures efficiently the process setpoints, assuring optimal and stable operation during continuous mode.