کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7149258 | 1462114 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Simultaneous detection of CMPA and PMPA, hydrolytes of soman and cyclosarin nerve agents, by nanopore analysis
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Simultaneous detection of CMPA and PMPA, hydrolytes of soman and cyclosarin nerve agents, by nanopore analysis Simultaneous detection of CMPA and PMPA, hydrolytes of soman and cyclosarin nerve agents, by nanopore analysis](/preview/png/7149258.png)
چکیده انگلیسی
A sensitive nanopore-based analytical method was developed for the detection of cyclohexyl methylphosphonic acid (CMPA) and pinacolyl methylphosphonate (PMPA), hydrolytes of nerve agents soman and cyclosarin, respectively. The method uses a multi-functionalized α-hemolysin protein ion channel as the sensing element, with a host molecule β-cyclodextrin lodged in the lumen of the channel as a molecular adapter. The capture and release of CMPA/PMPA by the β-cyclodextrin host caused current modulations in the nanopore. Since the event residence times and amplitudes were significantly different, CMPA and PMPA could conveniently be differentiated and simultaneously quantitated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 176, January 2013, Pages 625-631
Journal: Sensors and Actuators B: Chemical - Volume 176, January 2013, Pages 625-631
نویسندگان
Jyoti Gupta, Qitao Zhao, Guihua Wang, Xiaofeng Kang, Xiyun Guan,