Key importance of compression properties in the biophysical characteristics of hyaluronic acid soft-tissue fillers

In conclusion, HA soft-tissue fillers exhibit widely different biophysical characteristics and many variables contribute to their overall performance. The elastic modulus G′ is not the only critical parameter to consider amongst the rheological properties: the compression parameters E′ and FN also provide key information, which should be taken into account for a better prediction of clinical outcomes, especially for predicting the volumising capacity and probably the ability to stimulate collagen production by fibroblasts.