کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7207940 | 1469084 | 2016 | 28 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Reinforcement of freeze-dried chitosan scaffolds with multiphasic calcium phosphate short fibers
ترجمه فارسی عنوان
تقویت داربست های کیتوزان یخ زده با الیاف کم فیبر کلسیم فسفات
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کلمات کلیدی
داربست استخوان، کیتوزان، کامپوزیت، الیاف کوتاه فسفات کلسیم، تقویت مکانیکی،
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
چکیده انگلیسی
The composite scaffolds of the chitosan and multiphasic calcium phosphate (HW) short fibers were prepared by freeze drying and characterized by X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM and FE-SEM). The mechanical properties of the scaffolds were assessed by compression test. The incorporation of HW fibers consisting three phases of hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP) and calcium pyrophosphate (CPP) into the chitosan matrices was associated with an increase in pore size, density and compressive strength and modulus, and a decrease in porosity and swelling ratio of the scaffolds. The strongest composite scaffolds in this study with a chitosan: HW fibers weight ratio of 1:1 showed a mean porosity of 69% and a mean strength and modulus of 420 kPa and 3.87 MPa, respectively. The in vitro bioactivity of the composites was confirmed by the formation of a calcium phosphate rich layer on the surface of soaked scaffolds in simulated body fluid. The findings of this initial work indicate that the chitosan-multiphasic calcium phosphate short fibers may be a suitable material for bone scaffolding.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 61, August 2016, Pages 590-599
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 61, August 2016, Pages 590-599
نویسندگان
Zahra Mohammadi, Abdorreza Sheikh-Mehdi Mesgar, Fariba Rasouli-Disfani,