کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7236354 1471092 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hydraulic permeability of meniscus fibrocartilage measured via direct permeation: Effects of tissue anisotropy, water volume content, and compressive strain
ترجمه فارسی عنوان
نفوذ پذیری هیدرولیکی فریباری منیزوک اندازه گیری شده از طریق نفوذ مستقیم: اثر ناهمسانگردی بافت، حجم آب و فشار فشاری
کلمات کلیدی
گوشت خوک، منیزوک، نفوذپذیری، فشرده سازی، ناهمسانگردی، بیومکانیک، حمل و نقل مایع،
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
Hydraulic permeability is an important material property of cartilaginous tissues, governing the rate of fluid flow, which is crucial to tissue biomechanics and cellular nutrition. The effects of strain, anisotropy, and region on the hydraulic permeability in meniscus tissue have not been fully elucidated. Using a one-dimensional direct permeation test, we measured the hydraulic permeability within statically compressed porcine meniscus specimens, prepared such that the explants were in either the axial or circumferential direction of either the central or horn (axial direction only) region of the medial and lateral menisci. A constant flow was applied and the pressure difference was measured using pressure transducers. Specimens were tested under 10-20% compressive strain. Permeability values were in the range of 1.53-1.87 × 10−15 m4/Ns, which is comparable to values found in the literature. Permeability was significantly anisotropic, being higher in the circumferential direction than in the axial direction. Additionally, there was a significant negative correlation between strain level and permeability for all groups. Lastly, no statistically significant difference was found between permeability coefficients from different regional locations. This study provides important information regarding structure-function relationships in meniscal tissues that helps to elucidate biomechanics and transport in the tissue, and can aid in the understanding of the tissue's role in the function of the knee joint and onset of osteoarthritis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 72, 27 April 2018, Pages 215-221
نویسندگان
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