کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7236951 1471098 2018 27 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simplified boundary conditions alter cortical-trabecular load sharing at the distal radius; A multiscale finite element analysis
ترجمه فارسی عنوان
شرایط مرزی ساده شده موجب تغییر بار کورتیک-ترابکولر در شعاع دفاعی می شود؛ تجزیه و تحلیل عنصر محدود چند عاملی
کلمات کلیدی
ریزساختار قارچ خوراکی، به اشتراک گذاری بار، چند منظوره، شرایط مرزی، تجزیه و تحلیل عنصر محدود،
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
High-resolution peripheral quantitative computed tomography (HR-pQCT) derived micro-finite element (FE) modeling is used to evaluate mechanical behavior at the distal radius microstructure. However, these analyses typically simulate non-physiologic simplified platen-compression boundary conditions on a small section of the distal radius. Cortical and trabecular regions contribute uniquely to distal radius mechanical behavior, and various factors affect these regions distinctly. Generalized strength predictions from standardized platen-compression analyses may not adequately capture region specific responses in bone. Our goal was to compare load sharing within the cortical-trabecular compartments between the standardized platen-compression BC simulations, and physiologic BC simulations using a validated multiscale approach. Clinical- and high-resolution images were acquired from nine cadaveric forearm specimens using an HR-pQCT scanner. Multiscale FE models simulating physiologic BCs, and micro-FE only models simulating platen-compression BCs were created for each specimen. Cortical and trabecular loads (N) along the length of the distal radius micro-FE section were compared between BCs using correlations. Principal strain distributions were also compared quantitatively. Cortical and trabecular loads from the platen-compression BC simulations were strongly correlated to the physiologic BC simulations. However, a 30% difference in cortical loads distally, and a 53% difference in trabecular loads proximally was observed under platen BC simulations. Also, distribution of principal strains was clearly different. Our data indicated that platen-compression BC simulations alter cortical-trabecular load sharing. Therefore, results from these analyses should be interpreted in the appropriate mechanical context for clinical evaluations of normal and pathologic mechanical behavior at the distal radius.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 66, 3 January 2018, Pages 180-185
نویسندگان
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