In vitro studies of heparin-coated magnetic nanoparticles for use in the treatment of neointimal hyperplasia

Cartoon representation of multifunctional iron oxide nanoparticle with catechol binding groups attached to a polyacrylic acid (PAA) backbone. This backbone was modified with heterobifunctional polyethylene oxide (PEO) stabilizers with heparin end groups. The resulting interactions with different cell lines is shown on the right-hand side of the graphic.86