Dual MRI T1 and T2(⁎) contrast with size-controlled iron oxide nanoparticles

Dual T1- and T2⁎-contrast imaging with SPION: (A-1) shows negative vessel/tissue contrasts from a FLASH acquisition after a SPIONhigh injection. (A-3) shows positively enhanced contrasts from a UTE acquisition for the corresponding rat. (A-2) shows fine vessels delineated in the head region by negative (top) and positive (bottom) contrast.256