کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
724045 892361 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
INVERSE METABOLIC ENGINEERING BY INTEGRATION OF MULTIPLE OMICS ANALYSES
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مکانیک محاسباتی
پیش نمایش صفحه اول مقاله
INVERSE METABOLIC ENGINEERING BY INTEGRATION OF MULTIPLE OMICS ANALYSES
چکیده انگلیسی

An inverse metabolic engineering method with “multiple omics analyses” was applied to creation of a stress tolerant strain of Saccharomyces cerevisiae. DNA microarray data of laboratory and brewing strains under high ethanol concentration condition (transcriptomics data) were compared and analyzed by a clustering method. Sensitivity analysis of gene knockout mutant library was further performed (phenomics data). The selection of candidate genes for conferring stress tolerance was successfully performed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IFAC Proceedings Volumes - Volume 40, Issue 4, 2007, Pages 19–24
نویسندگان
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