کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7249007 | 1471993 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The role of oxytocin receptor gene (OXTR) and mother's emotional warmth in predicting adulthood sociability
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The oxytocin receptor gene (OXTR) may function as a “plasticity gene” that increases or decreases sociability in those individuals susceptible to growing up in a beneficial versus more adverse environment. This study used data from 2289 (55% female) participants from the ongoing prospective Young Finns Study. Maternal emotional warmth was assessed in 1980 when the participants were 3-18 years old. Participants' sociability temperament was measured at five follow-ups, from 1992 to 2012. Emotional warmth in childhood and OXTR genotype were not directly associated with temperamental sociability. We found a nominally significant gene-environment interaction (p = .03) suggesting that participants with a genetic profile of rs1042778 T-allele and rs2254298 A-allele are affected high versus low emotional warmth, whereas homozygotes of both G-alleles are unaffected by the same environmental influence. Our findings should be, however, interpreted as a null result as the interaction effect did not survive correction for multiple testing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Personality and Individual Differences - Volume 125, 15 April 2018, Pages 74-79
Journal: Personality and Individual Differences - Volume 125, 15 April 2018, Pages 74-79
نویسندگان
Henrik Dobewall, Christian Hakulinen, Laura Pulkki-RÃ¥back, Ilkka Seppälä, Terho Lehtimäki, Olli T. Raitakari, Liisa Keltikangas-Järvinen, Mirka Hintsanen,