کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7268484 | 1473133 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy
ترجمه فارسی عنوان
یک مورد سیستم آتروفی- پارکینسونی چندگانه با اختلالات لکنت و پاللیالیا و آتروفی پوسته
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کلمات کلیدی
CVAUPDRSMSA-pTBIT2WIl-DOPA - L-DOPAsld - SldTraumatic brain injury - آسیب تروماتیک مغزMRI - امآرآی یا تصویرسازی تشدید مغناطیسیParkinson’s disease - بیماری پارکینسونT2-weighted imaging - تصویر برداری وزن T2Magnetic resonance imaging - تصویربرداری رزونانس مغناطیسیCerebrovascular accident - سکته مغزیbasal ganglia - عقدههای قاعدهایNeurogenic stuttering - لکنت نوروژنیکUnified Parkinson’s Disease Rating Scale - مقیاس درجه بندی بیماری بیماری پارکینسون متحدParkinsonism - پارکینسونیسمPutamen - پوسته، پوتامن
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
چکیده انگلیسی
Both developmental and acquired stuttering are related to the function of the basal ganglia-thalamocortical loop, which includes the putamen. Here, we present a case of stuttering- and palilalia-like dysfluencies that manifested as an early symptom of multiple system atrophy-parkinsonian type (MSA-P) and bilateral atrophy of the putamen. The patient was a 72-year-old man with no history of developmental stuttering who presented with a stutter for consultation with our otorhinolaryngology department. The patient was diagnosed with MSA-P based on parkinsonism, autonomic dysfunction, and bilateral putaminal atrophy revealed by T2-weighted magnetic resonance imaging. Treatment with levodopa improved both the motor functional deficits related to MSA-P and stuttering-like dysfluencies while reading; however, the palilalia-like dysfluencies were much less responsive to levodopa therapy. The patient died of aspiration pneumonia two years after his first consultation at our hospital. In conclusion, adult-onset stuttering- and palilalia-like dysfluencies warrant careful examination of the basal ganglia-thalamocortical loop, and especially the putamen, using neuroimaging techniques. Acquired stuttering may be related to deficits in dopaminergic function.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluency Disorders - Volume 57, September 2018, Pages 51-58
Journal: Journal of Fluency Disorders - Volume 57, September 2018, Pages 51-58
نویسندگان
Yoshikazu Kikuchi, Toshiro Umezaki, Taira Uehara, Hiroo Yamaguchi, Koji Yamashita, Akio Hiwatashi, Motohiro Sawatsubashi, Kazuo Adachi, Yumi Yamaguchi, Daisuke Murakami, Jun-ichi Kira, Takashi Nakagawa,