کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7284235 1474034 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Differences in early speech patterns between Parkinson variant of multiple system atrophy and Parkinson's disease
ترجمه فارسی عنوان
تفاوت در الگوهای گفتار زود هنگام در میان انواع مختلف پارکینسون آتروفی چندگانه و بیماری پارکینسون
کلمات کلیدی
آتروفی سیستم چندگانه، بیماری پارکینسون، سخنرانی - گفتار، تجزیه و تحلیل آکوستیک، تجزیه و تحلیل ادراکی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
چکیده انگلیسی
In Parkinson variant of multiple system atrophy (MSA-P), patterns of early speech impairment and their distinguishing features from Parkinson's disease (PD) require further exploration. Here, we compared speech data among patients with early-stage MSA-P, PD, and healthy subjects using quantitative acoustic and perceptual analyses. Variables were analyzed for men and women in view of gender-specific features of speech. Acoustic analysis revealed that male patients with MSA-P exhibited more profound speech abnormalities than those with PD, regarding increased voice pitch, prolonged pause time, and reduced speech rate. This might be due to widespread pathology of MSA-P in nigrostriatal or extra-striatal structures related to speech production. Although several perceptual measures were mildly impaired in MSA-P and PD patients, none of these parameters showed a significant difference between patient groups. Detailed speech analysis using acoustic measures may help distinguish between MSA-P and PD early in the disease process.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Language - Volume 147, August 2015, Pages 14-20
نویسندگان
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