کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7288761 | 1474173 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Repetitive transcranial magnetic stimulation induced slow wave activity modification: A possible role in disorder of consciousness differential diagnosis?
ترجمه فارسی عنوان
تحریک مغناطیسی ترانس مغناطیسی تکرار شده موجب تغییر فعالیت موج آهسته: نقش احتمالی در اختلال تشخیص افتراقی آگاهی می شود؟
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
چکیده انگلیسی
Slow wave activity (SWA) generation depends on cortico-thalamo-cortical loops that are disrupted in patients with chronic Disorders of Consciousness (DOC), including the Unresponsive Wakefulness Syndrome (UWS) and the Minimally Conscious State (MCS). We hypothesized that the modulation of SWA by means of a repetitive transcranial magnetic stimulation (rTMS) could reveal residual patterns of connectivity, thus supporting the DOC clinical differential diagnosis. We enrolled 10 DOC individuals who underwent a 24Â hh polysomnography followed by a real or sham 5Â Hz-rTMS over left primary motor area, and a second polysomnographic recording. A preserved sleep-wake cycle, a standard temporal progression of sleep stages, and a SWA perturbation were found in all of the MCS patients and in none of the UWS individuals, only following the real-rTMS. In conclusion, our combined approach may improve the differential diagnosis between MCS patients, who show a partial preservation of cortical plasticity, and UWS individuals, who lack such properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Consciousness and Cognition - Volume 38, 15 December 2015, Pages 1-8
Journal: Consciousness and Cognition - Volume 38, 15 December 2015, Pages 1-8
نویسندگان
Laura Rosa Pisani, Antonino Naro, Antonino Leo, Irene Aricò, Francesco Pisani, Rosalia Silvestri, Placido Bramanti, Rocco Salvatore Calabrò,