Loss of emotional insight in behavioral variant frontotemporal dementia or “frontal anosodiaphoria”

► Loss of insight results from bvFTD, a disorder affecting the medial frontal area. ► These patients have anosodiaphoria, or indifference, rather than anosognosia. ► This anosodiaphoria may result from a loss of emotional updating. ► Loss of emotional updating particularly impacts on self-referential processes. ► Frontal anosodiaphoria is a failure to emotionally tag self-referent information.