کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7298789 1475122 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Losing memories during sleep after targeted memory reactivation
ترجمه فارسی عنوان
از دست دادن حافظه در هنگام خواب پس از واکنش مجدد هدفمند هدف
کلمات کلیدی
دوباره فعال سازی حافظه هدفمند، خواب فراموش کردن حافظه اپیزودیک،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
Targeting memories during sleep opens powerful and innovative ways to influence the mind. We used targeted memory reactivation (TMR), which to date has been shown to strengthen learned episodes, to instead induce forgetting (TMR-Forget). Participants were first trained to associate the act of forgetting with an auditory forget tone. In a second, separate, task they learned object-sound-location pairings. Shortly thereafter, some of the object sounds were played during slow wave sleep, paired with the forget tone to induce forgetting. One week later, participants demonstrated lower recall of reactivated versus non-reactivated objects and impaired recognition memory and lowered confidence for the spatial location of the reactivated objects they failed to spontaneously recall. The ability to target specific episodic memories for forgetting during sleep has implications for developing novel therapeutic techniques for psychological disorders such as PTSD and phobias.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 151, May 2018, Pages 10-17
نویسندگان
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