کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7300416 1475166 2014 42 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Human brainstem plasticity: The interaction of stimulus probability and auditory learning
ترجمه فارسی عنوان
پلاستیک انقباضی انسانی: تعامل احتمال محرک و یادگیری شنوایی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
Two forms of brainstem plasticity are known to occur: an immediate stimulus probability-based and learning-dependent plasticity. Whether these kinds of plasticity interact is unknown. We examined this question in a training experiment involving three phases: (1) an initial baseline measurement, (2) a 9-session training paradigm, and (3) a retest measurement. At the outset of the experiment, auditory brainstem responses (ABR) were recorded to two unfamiliar pitch patterns presented in an oddball paradigm. Then half the participants underwent sound-to-meaning training where they learned to match these pitch patterns to novel words, with the remaining participants serving as controls who received no auditory training. Nine days after the baseline measurement, the pitch patterns were re-presented to all participants using the same oddball paradigm. Analysis of the baseline recordings revealed an effect of probability: when a sound was presented infrequently, the pitch contour was represented less accurately in the ABR than when it was presented frequently. After training, pitch tracking was more accurate for infrequent sounds, particularly for the pitch pattern that was encoded more poorly pre-training. However, the control group was stable over the same interval. Our results provide evidence that probability-based and learning-dependent plasticity interact in the brainstem.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 109, March 2014, Pages 82-93
نویسندگان
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