Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors

► Inhibitory avoidance memory consolidation was examined in male Wistar rats. ► Post-training intra-central amygdala injection of ACPA impaired memory consolidation. ► Intra-CeA injections of either NMDA or d-AP5 did not affect memory consolidation. ► NMDA prevented, while d-AP5 increased the effect of ACPA on memory consolidation. ► ACPA impairs memory consolidation via NMDA receptors in the CeA.