A commercially available fluorescence chemosensor for copper ion and its application in bioimaging

The commercially available fluorescent probe, 1,8-diamino naphthalene with a naphthalene ring as a chromophore and two amino groups as binding sites has been developed for sensitive detection of copper ions by fluorescence spectrometer in aqueous solution. It displayed an excellent selectivity and sensitivity for Cu2+ over other metal ions. The mechanism is that the fluorescence of probe was quenched by the paramagnetic effect from spin–orbit coupling of the Cu2+ after probe coordinated with Cu2+, and mechanism was proved by ESI-MS. The probe can be used to react to Cu2+ in live cells, providing a potentially powerful approach for probing Cu2+ chemistry in biological system.

The commercially available fluorescent probe with a naphthalene ring as a chromophore and two amino groups as binding sites has been developed for sensitive detection of copper ions in aqueous solution. It displayed an excellent selectivity and sensitivity for Cu2+ over other metal ions, and mechanism was proved by ESI-MS. The probe can be used to react to Cu2+ in live cells, providing a potentially powerful approach for probing Cu2+ chemistry in biological system.Figure optionsDownload as PowerPoint slide