کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7585022 1492032 2018 38 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect-directed classification of biological, biochemical and chemical profiles of 50 German beers
ترجمه فارسی عنوان
طبقه بندی اثرات بیولوژیکی، بیوشیمیایی و شیمیایی 50 آبجو آلمانی
کلمات کلیدی
خوشه بندی مستقیم هدایت شده، اثر انگشت پروفایل خودکار زیستی مستقیم، تجزیه و تحلیل داده های چند متغیره، غذای سالم،
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Biological and biochemical fingerprints were investigated for the first time for the feasibility of effect-directed classification, and thus, to allow the choice of a distinct beer with regard to beneficial health effects. A high-performance thin-layer chromatography method was newly developed and combined with in situ effect-directed analysis for profiling 50 German beers for multipotent active compounds, and thus, their health-related potential. Discovered multipotent active zones were online eluted and characterized by high resolution mass spectrometry. For example, isoxanthohumol, iso-α-ad/n-humulone or its isomers, desdimethyl-octahydro-isocohumulone and ad/n-humulone were proven as antimicrobial compounds, isoxanthohumol as an acetylcholinesterase inhibitor, and isoxanthohumol and iso-α-ad/n-humulone or its isomers as radical scavengers. Investigating multivariate data analysis of effect-directed fingerprints for the first time, the pattern recognition and classification results showed the power of clustering non-alcoholic beers from other types of beer, or it showed the differentiation of dark and non-alcoholic beers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 260, 15 September 2018, Pages 344-353
نویسندگان
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