Vitexin-2-O-xyloside, raphasatin and (−)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells

► Synergism of vitexin-2-O-xyloside, raphasatin and (−)-epigallocatechin-3-gallate. ► Treatments are cytotoxic to colon cancer cells but not to normal human lymphocytes. ► Treatments trigger ROS generation before apoptosis in colon cancer cells.