Determination of selenium species in biota with an emphasis on animal tissues by HPLC-ICP-MS

When measuring Se concentrations by ICP-MS, carbon enhancement in the ICP plasma and isobaric inferences from chloride-, sulfur-, bromine and oxygen containing matrices need to be considered. The use of dynamic reaction cell or collision cell minimises or eliminates these interferences, but in practice few interferences coelute with Se species.