Voltammetric analysis of cocaine using platinum and glassy carbon electrodes chemically modified with Uranyl Schiff base films

Platinum and glassy carbon electrodes chemically modified with films of Schiff bases of [UO2(3-MeOSalen)(H2O)] · H2O and [UO2(5-MeOSalen)(H2O)] · H2O, to determine cocaine were developed. The stability of these films in aqueous solution containing 1.0 mol L− 1 KCl and HCl 1.0 mM in pH 3 as supporting electrolyte and conducted cyclic voltammetric analysis of cocaine in the same supporting electrolyte were investigated. A reversible interaction between cocaine and the working electrodes increased the original peak current of the surface-modifier, according to the employed species. The determination of cocaine using the developed electrodes depended linearly on cocaine concentration in the range 0.54-9.10 μmol L− 1, with amperometric sensitivities of 5.21 × 107 and 1.66 × 105 μA mol− 1 L, limits of quantification of 0.29 and 0.50 μmol L− 1, and limits of detection of 0.07 and 0.15 μmol L− 1, respectively.