Simultaneous determination of 13 quinolone antibiotic derivatives in wastewater samples using solid‐phase extraction and ultra performance liquid chromatography-tandem mass spectrometry

► Multi-residue method to identify and quantify quinolone antibiotics in wastewater ► SPE-UPLC-MS/MS allows for very low detection and quantification limits. ► Extraction procedure for amphoteric and acid quinolones in one single step ► Validation of the method: quality parameters, accuracy (trueness and precision) ► Study of the influence of matrix components (matrix effect study)