Fluorescence resonance energy transfer between ZnSe ZnS quantum dots and bovine serum albumin in bioaffinity assays of anticancer drugs

The schematic representation of ZnSe ZnS QDs for influence of binding affinities of anticancer drugs to BSA based on FRET theory. Here, ZnSe ZnS QDs could enhance the affinity of SAHA, DOC, BUCN, DOX and HCPT for BSA, but showed competitive effect of MTX and VCR for BSA. So the interaction between nanoparticles and drugs will be available on whether or not the nanoparticles affect drug transport in blood.