Discovery of dimethyl pent-4-ynoic acid derivatives, as potent and orally bioavailable DGAT1 inhibitors that suppress body weight in diet-induced mouse obesity model

Discovery of dimethyl pent-4-ynoic acid derivatives, as potent and orally bioavailable DGAT1 inhibitors that suppress body weight in diet-induced mouse obesity model

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 10, 1 June 2018, Pages 1686-1692

Tao Yu, Chengde Wu, NengYang Shih, Qi Li, Chichung Chan, He Pan, Dan Yao, Yan Pan, Wei Liang, Liang Shen, Hui Zhao, Jian Li, Shuhui Chen,