Solid lipid nanoparticles for hydrophilic biotech drugs: Optimization and cell viability studies (Caco-2 & HEPG-2 cell lines)

Cell viability of Caco-2 (A) and HepG2 (B) cells exposed to Softisan®100 Lipid Nanoparticles (at 1%, 2%, 5% and 10%, v/v, diluted in FBS-free culture media) prepared by double emulsion technique. Results are expressed as % of control (untreated cells), and are average values (n = 3) ± S.D.