Synthesis and antiproliferative effect of novel 4-thiazolidinone-, pyridine- and piperazine-based conjugates on human leukemic cells

A series of new 4-thiazolidinone-, pyridine- and piperazine-based conjugates were synthesized, characterized and screened for their anticancer activity against nalm6, k562 and Jurkat cell lines. Few of them showed good potency to induce apoptosis in leukemia cells.