Regioselective synthesis of polycyclic aza-oxa and aza-oxa-thia heteroarenes as Colo-205 and HepG2 carcinoma cells growth inhibitors

Tetra- and pentacyclic diheteroaryl[b,d]pyrans and diheteroaryl[c,e][1,2]diazepines were synthesized and studied their cytotoxicity and apoptosis through mitochondrial pathway against colo-205 and hepG2 carcinoma cells.