Synthesis, transformation and biological evaluation of 2,3-secotriterpene acetylhydrazones and their derivatives

Methyl 3(R)-(3′-acetyl-5′methyl-2′,3′-dihydro-1′,3′,4′-oxadiazyol-2′)-1-cyano-2,3′-seco-2norlup-20(29)-ene-28-oate 11a. Anti-VSV activity: EC50 0.62 μM. Cytotoxic activity: IC50 5.8-18.6 μM.