Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: Synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis

► Fourteen prenylated flavonoids were synthesized, twelve of them for the first time. ► Compounds 6, 15, 16 clearly demonstrated the best results in cell growth inhibition. ► Compounds 3 and 6 caused the highest increases in the % of cells in G1 phase. ► Compound 6 revealed a significant increase in the levels of apoptosis.