β-Cyclodextrin engineered γ-Fe2O3@ hydroxyapatite nanocomposite as a novel scaffold for the synthesis of phenacyl derivatives

Magnetic hydroxyapatite (HAp) is being widely investigated for various applications in medical engineering and nanocomposite for transformation reaction. The present work describes an efficient procedure for the synthesis of phenacyl derivatives employing a novel, green and magnetically retrievable nanocomposite via the grafting of β-cyclodextrin moieties on the magnetic hydroxyapatite surface, γ-Fe2O3@HAp-CD. The structure and composition of the nanocomposite was performed by different methods and analyzed by Infrared Spectroscopy (FT-IR), Field Emission Scanning Electron Microscopy (FE-SEM), transmission electron microscopy (TEM), Thermo-Gravimetric Analysis (TGA), X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS) and Brunauer Emmett Teller (BET) and vibrating sample magnetometry (VSM). Our results indicate that conjugation with β-CD improves the catalytic activity in the reaction.