کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7866308 1509132 2018 38 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gemcitabine-loaded gold nanospheres mediated by albumin for enhanced anti-tumor activity combining with CT imaging
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
پیش نمایش صفحه اول مقاله
Gemcitabine-loaded gold nanospheres mediated by albumin for enhanced anti-tumor activity combining with CT imaging
چکیده انگلیسی
In this study, gold nanospheres mediated by albumin with an approximate diameter of 10 nm were synthesized via the reduction of HAuCl4 utilizing bovine serum albumin (BSA) as a biotemplate. The as-prepared nanocarriers loaded with gemcitabine were applied for enhanced anti-tumor activity combining with CT imaging in vitro. It has been shown that the bare nanospheres were biocompatible while the drug-loaded ones exhibited obvious effects with efficiencies significantly greater than that of the free gemcitabine.234
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 89, 1 August 2018, Pages 106-118
نویسندگان
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