Easy fabrication of aligned PLLA nanofibers-based 2D scaffolds suitable for cell contact guidance studies

An easy, low-cost and fast wet processing-based method named ASB-SANS has been used to fabricate poly(l-lactic acid) (PLLA) highly ordered and hierarchically organized 2D nanofibrillar patterns. The patterns have been used as scaffolds to HeLa and NIH-3T3, evidencing pronounced capability of contact guidance.