کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7868983 1509162 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Computational local stiffness analysis of biological cell: High aspect ratio single wall carbon nanotube tip
ترجمه فارسی عنوان
تجزیه و تحلیل سختی محلی محاسبه سلول بیولوژیکی: نکته نانولوله کربن تک دیواره نسبتا بالا
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد بیومتریال
چکیده انگلیسی
This contribution develops the idea of using CNTs as an AFM tip in computational analysis of the biological cells. The proposed software was ABAQUS 6.13 CAE/CEL provided by Dassault Systems. Finite element analysis employed for each section and displacement of the nodes located in the contact area was monitored by using an output database (ODB). Mooney-Rivlin hyperelastic model of the cell allows the simulation to obtain a new method for estimating the stiffness and spring constant of the cell. Stress and strain curve indicates the yield stress point which defines as a vertical stress and plan stress. Spring constant of the cell and the local stiffness was measured as well as the applied force of CNT-AFM tip on the contact area of the cell. This reliable integration of CNT-AFM tip process provides a new class of high performance nanoprobes for single biological cell analysis. With greater understanding of the way in which mechanical properties of SWCNT-AFM, it may easily possible to continuously tune the selectivity and sensitivity of nanotubes in biological applications.105
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 59, 1 February 2016, Pages 636-642
نویسندگان
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