کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7870605 | 1509187 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Influence of the titania nanotubes dimensions on adsorption of collagen: An experimental and computational study
ترجمه فارسی عنوان
تأثیر ابعاد نانولولههای تیتانا بر جذب کلاژن: یک مطالعه تجربی و محاسباتی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
چکیده انگلیسی
To investigate the influence of the titanium nanotube (TiNT) diameters on the adsorption of collagen type I (Col-I), TiNTs with different diameters were prepared with anodization. The adsorption amount of Col-I on the different TiNTs substrates was evaluated by spectrophotometric measurement and immunofluorescence staining, respectively. The results showed that the diameters of TiNTs played a key role in the adsorption process of Col-I. TiNTs with diameters around 100Â nm displayed a higher adsorption amount and faster adsorption speed than that of 30Â nm TiNTs. Furthermore, more collagen molecules were aggregated in the tubes of 100Â nm TiNTs. Molecular dynamics simulation was performed to elucidate the adsorption mechanism. The simulation results confirmed that physical adsorption was the main driving force, including van der Waals force and hydrogen bond between Col-I molecules and TiNTs. The calculated interaction energies indicated that the TiNTs with bigger dimensions had higher interaction energies, thus leading to the higher collagen adsorption.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 34, 1 January 2014, Pages 410-416
Journal: Materials Science and Engineering: C - Volume 34, 1 January 2014, Pages 410-416
نویسندگان
Weihu Yang, Xingfeng Xi, Qichun Ran, Peng Liu, Yan Hu, Kaiyong Cai,