کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7887937 | 1509790 | 2018 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effects of laser patterning 10CeTZP-Al2O3 nanocomposite disc surfaces: Osseous differentiation and cellular arrangement in vitro
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The effects of laser patterning 10CeTZP-Al2O3 nanocomposite disc surfaces: Osseous differentiation and cellular arrangement in vitro The effects of laser patterning 10CeTZP-Al2O3 nanocomposite disc surfaces: Osseous differentiation and cellular arrangement in vitro](/preview/png/7887937.png)
چکیده انگلیسی
Customized square grid arrangements of different groove depths (1.0, 1.5 and 3.0â¯Âµm) and separations (10 and 30â¯Âµm) were successfully laser patterned, using a nanosecond pulsed fibre laser, on the surface of 10â¯mol% ceria-stabilized zirconia and alumina (10CeTZP-Al2O3) nanocomposite discs (diameter: 10â¯mm; thickness: 1.5â¯mm). The patterned surfaces and the in vitro biological response of osteoblasts (SAOS-2) towards them were thoroughly analysed. In terms of composition, the laser treatment was found to cause superficial monoclinic-tetragonal zirconia phase transformation and alumina evaporation. In vitro, the most effective grid configuration for osseous differentiation was found to be 1.5â¯Âµm groove depth and 10â¯Âµm groove separation, and confocal microscopy revealed that the cells show a tendency to be sorted as groove depth increases. It is thought that custom-made patterns could be produced to guide cell attachment in vivo, which could favour implant integration and reduce healing time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ceramics International - Volume 44, Issue 8, 1 June 2018, Pages 9472-9478
Journal: Ceramics International - Volume 44, Issue 8, 1 June 2018, Pages 9472-9478
نویسندگان
Lidia Goyos-Ball, Catuxa Prado, Raquel DÃaz, Elisa Fernández, Arnold Ismailov, Tero Kumpulainen, Erkki Levänen, Ramón Torrecillas, Adolfo Fernández,