کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7924144 | 1511938 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Magnesium oxide-poly(ε-caprolactone)-chitosan-based composite nanofiber for tissue engineering applications
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
مواد الکترونیکی، نوری و مغناطیسی
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چکیده انگلیسی
The ability to produce composite nanofibers of inorganic particles and synthetic polymers represents a significant advancement in the development of composite materials for potential biomedical applications. In this study, composite nanofibers of magnesium oxide (MgO), poly(ε-caprolactone) (PCL) and chitosan (CS) with diameters in the range of 0.7-1.3â¯Âµm were fabricated by electrospinning their blend solutions in trifluroethanol and water. To support the potential use of these nanofibrous membranes for biomedical applications their physicochemical properties such as morphology, mechanical strength, and integrity in aqueous medium, were studied. Cellular compatibility was determined using cell viability assays and microscopy imaging, with the results showing that the nanofibrous membranes support 3T3 cell viability and attachments. The new composite nanofibrous membranes developed in this study have the ability to mimic the physical structure and function of tissue extracellular matrix (ECM) and thus have potential for many tissue engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: B - Volume 228, February 2018, Pages 18-27
Journal: Materials Science and Engineering: B - Volume 228, February 2018, Pages 18-27
نویسندگان
Nava P. Rijal, Udhab Adhikari, Shalil Khanal, Devdas Pai, Jagannathan Sankar, Narayan Bhattarai,