کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7924144 1511938 2018 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Magnesium oxide-poly(ε-caprolactone)-chitosan-based composite nanofiber for tissue engineering applications
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد مواد الکترونیکی، نوری و مغناطیسی
پیش نمایش صفحه اول مقاله
Magnesium oxide-poly(ε-caprolactone)-chitosan-based composite nanofiber for tissue engineering applications
چکیده انگلیسی
The ability to produce composite nanofibers of inorganic particles and synthetic polymers represents a significant advancement in the development of composite materials for potential biomedical applications. In this study, composite nanofibers of magnesium oxide (MgO), poly(ε-caprolactone) (PCL) and chitosan (CS) with diameters in the range of 0.7-1.3 µm were fabricated by electrospinning their blend solutions in trifluroethanol and water. To support the potential use of these nanofibrous membranes for biomedical applications their physicochemical properties such as morphology, mechanical strength, and integrity in aqueous medium, were studied. Cellular compatibility was determined using cell viability assays and microscopy imaging, with the results showing that the nanofibrous membranes support 3T3 cell viability and attachments. The new composite nanofibrous membranes developed in this study have the ability to mimic the physical structure and function of tissue extracellular matrix (ECM) and thus have potential for many tissue engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: B - Volume 228, February 2018, Pages 18-27
نویسندگان
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