Mechanical and hyperthermic properties of magnetic nanocomposites for biomedical applications

• Magnetic nanoparticle (γ-Fe2O3) filled poly-dimethylsiloxane nanocomposites were fabricated using soft lithography method.
• Their mechanical and hyperthermic properties were studied as a function of the weight fraction of γ-Fe2O3.
• Increasing weight fraction of γ-Fe2O3 increases Young’s modulus but decreases strength.
• Heat generation within alternating magnetic field increases with weight fraction of γ-Fe2O3.
• These enhanced properties can be exploited for the development of biomedical devices such as lab-on chip and hyperthermic thermoseeds/probes.

An understanding of the properties of multifunctional materials is important for the design of devices for biomedical applications. In this paper, a combination of experiments and models was used to study the mechanical and hyperthermic properties of magnetic nanoparticles (MNP)-filled PDMS composites for biomedical applications. These are studied as a function of the weight of MNP, γ-Fe2O3. The results showed the effects on mechanical behavior, and specific losses in a magnetic field. The measured Young’s moduli are in good agreement with the moduli predicted from the Bergström–Boybce model. Specific losses calculated from magnetic measurements are used to predict the thermal dose under in-vivo conditions. The implications of the results were discussed for potential applications in biomedical devices

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