Reactor production of Thorium-229

Limited availability of 229Th for clinical applications of 213Bi necessitates investigation of alternative production routes. In reactor production, 229Th is produced from neutron transmutation of 226Ra, 228Ra, 227Ac and 228Th. Irradiations of 226Ra, 228Ra, and 227Ac targets at the Oak Ridge National Laboratory High Flux Isotope Reactor result in yields of 229Th at 26 days of 74.0±7.4 MBq/g, 260±10 MBq/g, and 1200±50 MBq/g, respectively. Intermediate radionuclide yields and cross sections are also studied.