Sialylation of Integrin β1 is Involved in Radiation-Induced Adhesion and Migration in Human Colon Cancer Cells

The increase of integrin β1 sialylation by ST6 Gal I is critically involved in radiation-mediated adhesion and migration of colon cancer cells. From these findings, integrin β1 sialylation may be a novel target for overcoming radiation-induced survival, especially radiation-induced adhesion and migration.