Effect of S-Phase Kinase-Associated Protein 2 Expression on Distant Metastasis and Survival in Nasopharyngeal Carcinoma Patients

The results of our study have shown that Skp2 expression is frequent in NPC and has a wide range of distribution in H-score. Skp2 overexpression is significantly predictive of DMF survival and OS, independent of the T stage and/or older age. Therefore, Skp2 might represent a useful prognostic adjunct to risk stratify NPC patients for appropriate allocation of adjuvant therapy.