دانلود مقالات ISI درباره Skp2 + ترجمه فارسی

27-hydroxycholesterol: A novel player in molecular carcinogenesis of breast and prostate cancer

Keywords: 27-OHC; 27-hydroxycholesterol; ADT; androgen deprivation therapy; AR; androgen receptor; ATF4; Activating Transcription Factor 4; ATF6; Activating Transcription Factor 6; C/EBP; CCAAT / Enhancer binding proteins; CHOP; C/EBP homologous protein; CIP2A; can

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Forkhead Box O (FOXO) transcription factor in aging and diseases

Keywords: FOXO; Forkhead box O; DBD; DNA-binding domain; NLS; Nuclear localization sequence; NES; Nuclear export sequence; IRE; Insulin-responsive element; ARDs; Age-related diseases; RTK; Receptor tyrosine kinase; PI3K; Phosphoinositide 3kinase; SGK; Serum and glu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Melanoma antigen-D2 controls cell cycle progression and modulates the DNA damage response

Keywords: APC/C; anaphase-promoting complex or cyclosome; ATM; ataxia-telangiectasia mutated protein; ATR; ataxia-telangiectasia- and rad3-related protein; CDC20; cell division cycle protein 20; CDK; cyclin-dependent kinase; CHK1; checkpoint kinase 1; CHK2; checkpo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis

Keywords: Cutaneous T-cell lymphoma; 9-cis UAB30; Bexarotene; SKP2; p27kip1; PSMA7;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases

Keywords: ALS; amyotrophiclateral sclerosis; AP-1; activator protein 1; APC; antigen-presenting cell; APC/C; anaphase promoting complex/cyclosome; CLR; C-type lectin receptor; CRL; Cullin RING ligase; ERK; extracellular signalregulated kinase; FANC; Fanconi anemia

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

A novel selenonucleoside suppresses tumor growth by targeting Skp2 degradation in paclitaxel-resistant prostate cancer

Keywords: CRPC; castration-resistant prostate cancer; PI3K; Phosphatidylinositol-4,5-bisphosphate 3 kinase; PTEN; Phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; BrdU; bromodeoxy-uridine; FITC; Fluorescein isothiocyanate; Skp2; S phase kinase-a

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Tetrandrine inhibits deregulated cell cycle in pancreatic cancer cells: Differential regulation of p21Cip1/Waf1, p27Kip1 and cyclin D1

Keywords: Tetrandrine; Pancreatic cancer; Cell cycle inhibition; p27Kip1; p21Cip1/Waf1; Skp2;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-365 accelerates cardiac hypertrophy by inhibiting autophagy via the modulation of Skp2 expression

Keywords: MicroRNA-365 (miR-365); Skp2; Autophagy; Cardiac hypertrophy; mTORC1 signaling;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Melanoma antigen-A11 regulates substrate-specificity of Skp2-mediated protein degradation

Keywords: Androgen receptor; Melanoma antigen-A11; MAGE-A11; Skp2; Cyclin A; E2F1; MAGE-A11; melanoma-antigen-A11; AR; androgen receptor; shRNA; short hairpin RNA; Skp2; S phase kinase-associated protein; SCF; Skp1-Cullin1-F-box; cdk; cyclin-dependent kinase; R1881

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Amentoflavone suppresses tumor growth in ovarian cancer by modulating Skp2

Keywords: Amentoflavone; Ovarian cancer; Skp2; AMPK;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleN-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc

Keywords: NDRG1; Cancer initiating cells; Lung cancer; c-Myc; Skp2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionRegulation of p27 by ubiquitin ligases and its pathological significance in human lung carcinomas

Keywords: Lung cancer; p27; Ubiquitin ligase; Skp2; KPC; Pirh2;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Danshen improves survival of patients with colon cancer and dihydroisotanshinone I inhibit the proliferation of colon cancer cells via apoptosis and skp2 signaling pathway

Keywords: NHIRD; National Health Insurance Research Database; NHI; National Health Insurance; CRC; Colorectal cancer; Skp2; S-phase kinase-associated protein 2; CCL2; CC chemokine ligand 2; TAMs; tumor-associated macrophages; TCM; Traditional Chinese Medicine; FHPs

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

BAG3 promotes proliferation of ovarian cancer cells via post-transcriptional regulation of Skp2 expression

Keywords: BAG3; Skp2; miR-21-5p; Ovarian cancer cells;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication

Keywords: PGs; Cyclopentenone prostaglandins; DISC; Death-inducing signal complex; DUBs; Deubiquitinating enzymes; EMT; Epithelial-mesenchymal transition; IAPs; Inhibitor of apoptosis protein; IDs; Inhibitor of differentiation/DNA binding; MMPs; Matrix metalloprote

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of AMPK inhibits PDGF-induced pulmonary arterial smooth muscle cells proliferation and its potential mechanisms

Keywords: Pulmonary arterial smooth muscle cells; AMPK; mTOR; p27; Skp2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

Keywords: E3 ubiquitin ligase; Cullin RING ligase; Ubiquitin-proteasome system; Therapeutic targets; ASB; ankyrin repeat-containing proteins with a SOCS box; β-Trcp; β-transducin repeat-containing protein; BTB; bric-a-brac; CIS1; cytokine-inducible Src homology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of AMPK α2 inhibits airway smooth muscle cells proliferation

Keywords: LY294002 (PubChem CID: 11957589); Rapamycin (PubChem CID: 5284616)AMPK; Airway smooth muscle cells; MTOR; Skp2; P27

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2

Keywords: Runx2; Osteoblast; Skp2; Polyubiquitination; Osteogenesis;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Skp1: Implications in cancer and SCF-oriented anti-cancer drug discovery

Keywords: Arf6; ADP-ribosylation factor 6; BIMEL; extra-long isoform of BIM; β-TRCP; β-transducin repeat-containing protein; CDCA3; cell division cycle associated 3; CDK; cyclin-dependent kinase; CENP-E; centrosome-associated protein E; Cks1; cyclin-dependent pro

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Erbin loss promotes cancer cell proliferation through feedback activation of Akt-Skp2-p27 signaling

Keywords: Erbin; Akt; Skp2; p27; Cell proliferation; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Sulforaphane down-regulates SKP2 to stabilize p27KIP1 for inducing antiproliferation in human colon adenocarcinoma cells

Keywords: Sulforaphane; Antiproliferation; SKP2; p27KIP1; Colon adenocarcinoma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway

Keywords: Arid4a; AT rich interactive domain 4A; cDNA; complementary DNA; cgr; Cricetulus griseus; CHO; Chinese hamster ovary; Dcun1d1; defective in cullin neddylation 1, domain containing 1; miRNA; microRNA; mmu; Mus musculus; ncRNA; non-coding RNA; pDNA; plasmid

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Downregulation of POLD4 in Calu6 cells results in G1-S blockage through suppression of the Akt-Skp2-p27 pathway

Keywords: POLD4; Lung cancer; Checkpoint; Skp2; DNA replication; DNA repair;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

IKK-β/NF-κB p65 mediates p27Kip1 protein degradation in arsenite response

Keywords: IKKβ; IκB kinase β; NF-κB; nuclear factor κB; Skp2; S-phase kinase associated protein 2; Kpc; Kip1 ubiquitination-promoting complex; CHX; cyclohexamide; GSK3; glycogen synthase kinase 3; Cul4a; Culin 4A, a core component for a ubiquitin ligase; Ro52;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

p27 is regulated independently of Skp2 in the absence of Cdk2

Keywords: Cyclin-dependent kinase; Knockout mice; Cdk2; Skp2; p27;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The links between AKT and two intracellular proteolytic cascades: Ubiquitination and autophagy

Keywords: BRCA1; breast cancer susceptibility gene 1; BRCT; Brca1 C-terminal; CHIP; chaperone-associated ubiquitin ligase; CYLD; cylindromatosis; DAPK; death-associated protein kinase; DUB; deubiquitinating enzyme); EGF; epidermal growth factor; FADD; fas-associate

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis

Keywords: COP9 signalosome; F-box proteins; Preadipocytes; p27; Skp2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells

Keywords: Ace-tubulin; Acetylated-tubulin; ANOVA; analysis of variance; DAPI; 4′,6-diamidino-2-phenylindole; E-cad; E-cadherin; ELISA; enzyme-linked immunosorbent assay; FAK; focal adhesion kinase; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Downregulation of Ezh2 methyltransferase by FOXP3: New insight of FOXP3 into chromatin remodeling?

Keywords: Ezh2; enhancer of zeste homolog 2; H3K27me3; trimethylation of histone H3 lysine 27; HDAC; histone deacetylase; miR-101; microRNA-101; SATB1; special AT-rich sequence binding protein 1; SKP2; S-phase kinase-associated protein 2; FOXP3; Ezh2; Praja1; Trans

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of the MIR155 host gene in physiological and pathological processes

Keywords: 3T3-L1; cell line derived from 3T3 cells; 3′-UTR; 3′-untranslated region; AICDA; activation-induced cytidine deaminase; AML; acute myeloid leukemia; Ang II; angiotensin II; AP-1; activator protein 1; AT1R; angiotensin II type 1 receptor; BACH1; basic

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2013 سفارش ترجمه

Cdh1 inhibits reactive astrocyte proliferation after oxygen–glucose deprivation and reperfusion

Keywords: Anaphase-promoting complex; Cdh1; Astrocytes; Cell proliferation; Ischemia; Skp2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27Kip1

Keywords: Emi1; Hepatocellular carcinoma; p27Kip1; Skp2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Histone acetyltransferase hMOF promotes S phase entry and tumorigenesis in lung cancer

Keywords: hMOF; H4K16 acetylation; Skp2; Cell cycle; Tumorigenesis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Deregulation of the COP9 signalosome–cullin-RING ubiquitin-ligase pathway: Mechanisms and roles in urological cancers

Keywords: COP9 signalosome; Cullin-RING ubiquitin ligases; Skp2; Urological cancer; microRNAs; Tumor therapyβ-TrCP, β-transducin repeat-containing protein; CAND1, cullin-associated NEDD8-dissociated protein 1; CSN, COP9 signalosome; CRL, cullin-RING ubiquitin ligas

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Distinct and specific roles of AKT1 and AKT2 in androgen-sensitive and androgen-independent prostate cancer cells

Keywords: Proliferation; Migration; Cell cycle; p27; skp2; Prostate cancer

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Stat3 induces oncogenic Skp2 expression in human cervical carcinoma cells

Keywords: Cervical carcinoma; Stat3; Skp2; Protein degradation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Skp2: A novel potential therapeutic target for prostate cancer

Keywords: Skp2; Prostate cancer; p27; Androgen receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Cycle arrest and apoptosis in MDA-MB-231/Her2 cells induced by curcumin

Keywords: Curcumin; Skp2; Her2; BT483 cells; MDA-MB-231/Her2 cells;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Clinicopathologic significance and function of S-phase kinase-associated protein 2 overexpression in hepatocellular carcinoma

Keywords: Hepatocellular carcinoma; SKP2; Prognosis; RNA interference; Cell cycle;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Prognostic Value of Chromosomal Imbalances in Squamous Cell Carcinoma and Adenocarcinoma of the Lung

Keywords: AC; adenocarcinoma; A-CDK2; active cyclin-dependent kinase 2; ANCA; average number of copy alterations; APC; Adenomatous Polyposis coli; ARG; Abelson-related oncogene; CGH; comparative genomic hybridization; CI; confidence interval; DNA; deoxyribonucleic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The impact of Skp2 overexpression on recurrence-free survival following radical prostatectomy

Keywords: Skp2; Biomarker; Prostate cancer; Recurrence

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The hallmarks of CDKN1C (p57, KIP2) in cancer

Keywords: AML; acute myeloid leukemia; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-x long; BCR-ABL; breakpoint cluster region-V-abl Abelson murine leukemia viral oncogene homolog 1; bHLH; basic helix-loop-helix; BWS; Beckwith-Wiedemann Syndrome; CDK; cy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

p38 MAPK regulates G1-S transition in hypoxic cardiac fibroblasts

Keywords: Cardiac fibroblasts; Hypoxia; Cell cycle regulation; p38 MAPK; p27; Skp2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Damage-specific DNA binding protein 1 (DDB1) is involved in ubiquitin-mediated proteolysis of p27Kip1 in response to UV irradiation

Keywords: Damage-specific DNA binding protein 1; UV irradiation; DNA damage; CDK inhibitor p27Kip1; E3-ubiquitin-ligase; DDB1/DDB2; damage-specific DNA binding protein 1/2; Skp2; S-phase kinase-associated protein 2; CUL4A; cullin 4A; CDK; cyclin-dependent kinase; G

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Cks85A and Skp2 interact to maintain diploidy and promote growth in Drosophila

Keywords: Cell cycle; Drosophila; SCF; Skp2; Cks; Genome instability;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation of Skp2

Keywords: ADT; androgen deprivation therapy; AIPC; androgen-independent prostate cancer; AR; androgen receptor; CS; charcoal-stripped fetal bovine serum; EMT; epithelial-to-mesenchymal transition; HP1β; heterochromatin protein 1β; IL-8; interleukin-8; IGFBP3; ins

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells

Keywords: Matrix metalloproteinases; Skp2; Sp1; Cell invasion

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Histologic-Type Specific Role of Cell Cycle Regulators in Non-Small Cell Lung Carcinoma

Keywords: cell cycle; non-small cell lung carcinoma; prognosis; p27; Cks1; Skp2; PTEN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه