A Model of Reoxygenation Dynamics of Head-And-Neck Tumors Based on Serial 18F-Fluoromisonidazole Positron Emission Tomography Investigations

Conclusion: A tumor control probability model was developed based on repeated FMISO PET scans during RT. The model combines the local perfusion efficiency and the degree of hypoxia to estimate reoxygenation time. It constitutes a key for hypoxia image-guided dose escalation in RT.