Reduction of Normal Lung Irradiation in Locally Advanced Non-Small-Cell Lung Cancer Patients, Using Ventilation Images for Functional Avoidance

Conclusions: Four-dimensional computed tomography-derived ventilation regions were successfully used as avoidance structures to reduce the DVH and DFH at 5 Gy in all cases. In a subset, there was also a reduction in the F10 and V10 without a change in the V20, suggesting that this technique could be safely used.