Multifractality in cerebrovascular dynamics: an approach for mechanisms-related analysis

We consider here an approach for multifractal analysis of cerebrovascular dynamics that provides a relation between the occurred changes in the blood flow velocity and the physiological mechanisms of cerebral regulation. We apply this approach to study responses of the cerebral dynamics in rats to variations in the peripheral blood pressure and show that these responses are essentially different for large and small vessels. We conclude that the acute peripheral hypertension is accompanied by changes in the multifractal properties of the microcerebral dynamics associated with the NO-related endothelial function.