کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8258184 | 1534445 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Corticospinal and intracortical excitability of the quadriceps in active older and younger healthy adults
ترجمه فارسی عنوان
تحریک پذیری کورتیکاسپالین و داخل کورتیکی چهارگوشه در بزرگسالان سالم و سالم فعال
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کلمات کلیدی
تحریک مغناطیسی ترانس مغناطیسی، عضله، سالخورده، الکترومیوگرافی، موتور منجر به پتانسیل،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
چکیده انگلیسی
Age-related declines in neuromuscular function are well-documented, though the mechanisms underlying these deficits are unclear. Specific changes in corticospinal and intracortical neurophysiology may contribute, but have not been well studied, especially in lower extremity muscles. Furthermore, variations in physical activity levels may potentially confound the interpretation of neurophysiologic findings. Therefore, the purpose of this study was to quantify differences in transcranial magnetic stimulation (TMS) measures of corticospinal and intracortical excitability of the quadriceps between healthy, active older and younger adults. Twenty younger (age: 25.2 ± 2.4 years; body mass index [BMI]: 22.1 ± 3.0 kg/m2; 11 males and 9 females) and twenty older (age: 67.7 ± 5.5 years; BMI: 26.8 ± 3.8 kg/m2; 11 males and 9 females) subjects who exercised regularly (at least 30 min, 3 times/week) completed testing. Motor evoked potentials (MEPs) were measured by superficial electromyographic recordings of the vastus lateralis (VL). Measures of corticospinal excitability using a double cone TMS coil included resting motor thresholds (RMT), resting recruitment curves (RRCs) and silent periods (SP). Intracortical excitability was measured using paired pulse paradigms for short interval intracortical inhibition (SICI) and intracortical facilitation (ICF). No statistically significant differences between older and younger adults were found for RMT, RRC slopes, SP, SICI or ICF measures (p > 0.05). The physically active nature of the older adults included in this study may have contributed to the lack of differences in corticospinal and intracortical excitability since physical activity in older adults attenuates age-related declines in neuromuscular function.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Gerontology and Geriatrics - Volume 56, Issue 1, JanuaryâFebruary 2013, Pages 279-284
Journal: Archives of Gerontology and Geriatrics - Volume 56, Issue 1, JanuaryâFebruary 2013, Pages 279-284
نویسندگان
Jennifer E. Stevens-Lapsley, Abbey C. Thomas, James B. Hedgecock, Benzi M. Kluger,