کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
826272 907914 2014 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Inflammatory breast cancer: New factors contribute to disease etiology: A review
ترجمه فارسی عنوان
سرطان پستان التهابی: عوامل جدید به علت بیماری علل بیماری: بررسی
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
چکیده انگلیسی

Inflammatory breast cancer (IBC) is a highly metastatic and fatal form of breast cancer. In fact, IBC is characterized by specific morphological, phenotypic, and biological properties that distinguish it from non-IBC. The aggressive behavior of IBC being more common among young women and the low survival rate alarmed researchers to explore the disease biology. Despite the basic and translational studies needed to understand IBC disease biology and identify specific biomarkers, studies are limited by few available IBC cell lines, experimental models, and paucity of patient samples. Above all, in the last decade, researchers were able to identify new factors that may play a crucial role in IBC progression. Among identified factors are cytokines, chemokines, growth factors, and proteases. In addition, viral infection was also suggested to participate in the etiology of IBC disease. In this review, we present novel factors suggested by different studies to contribute to the etiology of IBC and the proposed new therapeutic insights.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Advanced Research - Volume 5, Issue 5, September 2014, Pages 525–536
نویسندگان
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